Semax and NAD+ offer a range of benefits for patients, primarily supporting cognitive function, neuroprotection, recovery from neurological injury, and mood regulation. Its effects are well-documented in clinical and experimental settings.
Key Benefits for Patients
- Cognitive Enhancement: Semax and NAD+ improves memory formation, recall, attention span, focus, and learning capacity. It enhances both executive function and mental processing speed.
- Neuroprotection & Recovery: It protects neurons from ischemia, oxidative stress, and injury, promotes neural regeneration, and accelerates recovery after stroke, traumatic brain injury, or hypoxic events.
- Mood and Stress Regulation: Semax and NAD modulates dopamine and serotonin pathways, supporting emotional resilience and reducing symptoms of mild to moderate depression or anxiety
- Improved Cerebral Blood Flow: It increases blood flow and oxygenation in the brain, supporting optimal neural activity and aiding recovery after acute neurological insult.
- ADHD & Executive Dysfunction: Emerging research and clinical use support its benefit for attention-deficit/hyperactivity disorder (ADHD) and executive dysfunction without typical stimulant side effects.
Clinical Conditions and Applications:
- Stroke & Traumatic Brain Injury: Used to speed up neurological recovery, minimize long-term deficits, and protect brain tissue after acute injury.
- ADHD and Cognitive Decline: Shown potential for improving symptoms in ADHD and attention disorders, as well as offering cognitive support in early dementia or after hypoxic injuries.
- Chronic Neurodegenerative Diseases: Investigated as supportive therapy in conditions like Parkinson’s disease, ALS, and Alzheimer’s due to its neuroprotective and anti-inflammatory effects.
- Addiction Recovery: Sometimes prescribed as adjunct support for opioid or alcohol withdrawal, due to its mood and cognitive stabilizing effects.
- General Cognitive Maintenance: Used off-label for cognitive enhancement in competitive, high-stress, or recovery-based environments.
- BDNF Upregulation: Promotes neuroplasticity and neuronal resilience by increasing brain-derived neurotrophic factor (BDNF).
- Neurotransmitter Modulation: Enhances and balances dopamine and serotonin activity, aiding motivation, focus, and mood.
- Antioxidant & Anti-inflammatory Actions: Reduces inflammation and oxidative damage in neural tissues, protecting against injury.
Semax
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3987924/
- https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Semax-Cognitive-Vitality-For-Researchers.pdf
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6787556/